Notes
| Embase <1974 to 2022 October 27> Ovid MEDLINE(R) ALL <1946 to October 27, 2022> 1 exp Benzodiazepines/ or (12794-10-4 or benzodiazepin* or m0q7802g2b).tw,kf. 2 Alprazolam/ or ("28981-97-7 (alprazolam)" or alprazolam or alprazolan or alprox or apo alpraz or apo-alpraz or cassadan or d-65mt or d65mt or esparon or kalma or niravam or novo alprazol or novo-alprazol or nu alpraz or nu-alpraz or ralozam or tafil or trankimazin or u-31,889 or u31,889 or xanax or yu55mq3izy).tw,kf. 3 exp Benzodiazepinones/ or benzodiazepinon*.tw,kf. 4 Anthramycin/ or (0wzd9y66wn or "35599-87-2 ((11a alpha)-isomer)" or "4803-27-4 (anthramycin)" or anthramycin* or "anthramycin, (11a alpha)-isomer" or antramycin*).tw,kf. 5 Bromazepam/ or ("1812-30-2 (bromazepam)" or anxyrex or bromalich or bromaz* or durazanil or lectopam or lexatin or lexomil or lexotan or lexotanil or ro 5-3350 or ro 53350 or x015l14v0o).tw,kf. 6 Clonazepam/ or ("1622-61-3 (clonazepam)" or "2h-1,4-benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-" or 5pe9fde8gb or antelepsin or clonazepam* or klonopin or rivotril or ro 5-4023 or ro 54023).tw,kf. 7 Devazepide/ or ("103420-77-5 (devazepide)" or devazepide* or je6p7qy7nh or l 364,718 or l-364,718 or l364,718 or mk 329 or mk-329 or mk329).tw,kf. 8 Diazepam/ or ("439-14-5 (diazepam)" or 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one or apaurin or diazemuls or diazepam or diastat or faustan or q3jtx2q7tu or relanium or seduxen or sibazon or stesolid or valium).tw,kf. 9 Nordazepam/ or ("1088-11-5 (nordazepam)" or 67220mcm01 or calmday or dealkylprazepam or demethyldiazepam or deoxydemoxepam or desmethyldiazepam or n desalkylhalazepam or n descyclopropylmethyl prazepam or n descyclopropylmethylprazepam or n destrifluoroethylhalazepam or n-desalkylhalazepam or n-descyclopropylmethyl-prazepam or n-descyclopropylmethylprazepam or n-destrifluoroethylhalazepam or nordaz or nordazepam or nordiazepam or norprazepam or ro 5 2180 or ro 5-2180 or ro 52180 or tranxilium n or vegesan).tw,kf. 10 Flumazenil/ or (40p7xk9392 or "78755-81-4 (flumazenil)" or anexate or flumazenil or flumazepil or lanexat or ro 15 1788 or ro 15-1788 or ro 151788 or romazicon).tw,kf. 11 Flunitrazepam/ or ("1622-62-4 (flunitrazepam)" or 620x0222fq or fluni 1a pharma or flunibeta or flunimerck or fluninoc or flunitrazepam or flunizep von ct or fluridrazepam or narcozep or ro-5-4200 or ro54200 or rohipnol or rohypnol or von ct, flunizep).tw,kf. 12 Flurazepam/ or ("1172-18-5 (di-hcl)" or "121531-42-8 (mono-perchlorate)" or "17617-23-1 (flurazepam)" or "36105-20-1 (mono-hcl)" or 756rdm536m or 7c4jh842ij or dalmadorm or dalmane or dormodor or flurazepam or ihp475989u or somnol or staurodorm).tw,kf. 13 Lorazepam/ or ("846-49-1 (lorazepam)" or ativan or donix or duralozam or durazolam or idalprem or laubeel or lorazep von ct or lorazepam* or loreev or novo lorazem or novolorazem or nu loraz or nu-loraz or o26fzp769l or orfidal wyeth or sedicepan or sinestron or somagerol or temesta or tolid or von ct, lorazep or wy 4036 or wy-4036 or wy4036 or wyeth, orfidal).tw,kf. 14 Oxazepam/ or ("604-75-1 (oxazepam)" or 6gow6dwn2a or adumbran or oxpam or oxazepam or serax or tazepam).tw,kf. 15 Pirenzepine/ or (10ym403fls or 3g0285n20n or gastrotsepin or gastrozepin or l-s 519 or ls 519 or ls-519 or ls519 or piren basan or piren-basan or pirenzepin* or pyrenzepine or ulcoprotect or ulgescum).tw,kf. 16 Prazepam/ or ("2955-38-6 (prazepam)" or centrax or demetrin or lysanxia or mono demetrin or prazepam or q30vcc064m or reapam or sedapran or trepidan).tw,kf. 17 Temazepam/ or (3 hydroxydiazepam or 3-hydroxydiazepam or "846-50-4 (temazepam)" or chb1qd2qss or corax or dasuen or euhypnos or hydroxydiazepam or levanxol or medilium or methyloxazepam or nocturne or norkotral tema or normison or normitab or nortem or oxydiazepam or planum or pronervon t or remestan or restoril or ro 5 5345 or ro-5-5345 or ro55345 or sah 47 603 or sah 47-603 or sah 47603 or signopam or tema, norkotral or temaze or temazep von ct or temazepam or temtabs or tenox or von ct, temazep or wy 3917 or wy-3917 or wy3917).tw,kf. 18 Chlordiazepoxide/ or ("121531-47-3 (mono-hclo4)" or "14844-23-6 (hcl)" or "438-41-5 (mono-hcl)" or "56617-98-2 (hbr)" or "58-25-3 (chlordiazepoxide)" or 6rz6xez3cr or 7 chloro 2 methylamino 5 phenyl 3h 1,4 benzodiazepine 4 oxide or 7 chloro n methyl 5 phenyl 3h 1,4 benzodiazepin 2 amine 4 oxide or 7-chloro-2-methylamino-5-phenyl-3h-1,4-benzodiazepine-4-oxide or 7-chloro-n-methyl-5-phenyl-3h-1,4-benzodiazepin-2-amine 4-oxide or chlordiazepoxide or chlozepid or elenium or librium or mfm6k1xwdk or methaminodiazepoxide).tw,kf. 19 Clobazam/ or (1-phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3h-1,5-benzodiazepine or "22316-47-8 (clobazam)" or 2mro291b4u or clobazam or frisium or hr 376 or lm 2717 or lm-2717 or lm2717 or onfi or urbanyl).tw,kf. 20 Clorazepate Dipotassium/ or (4306-cb or "57109-90-7 (clorazepate dipotassium)" or 63fn7g03xy or chlorazepate or clorazepate or clorazepic acid or d51wo0g0l4 or dipotassium chlorazepate or ms63g8nqui or tranxene or tranxilium).tw,kf. 21 Estazolam/ or ("29975-16-4 (estazolam)" or 36s3eqv54c or d-40ta or d40ta or estazolam or nuctalon or prosom or tasedan).tw,kf. 22 Medazepam/ or ("2898-11-5 (mono-hcl)" or "2898-12-6 (medazepam)" or etm878jc9k or medazepam or nobrium or p0j3387w3s or ro 5 4556 or ro 5-4556 or ro 54556 or rudotel or rusedal).tw,kf. 23 Midazolam/ or (77520s18se or dormicum or midazolam or r60l0sm5bc or ro 21 3981 or ro 21-3981 or ro 213981 or versed or w7ttw573jj).tw,kf. 24 Olanzapine/ or ("2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno(2,3-b)(1,5)benzodiazepine" or olanzapine pamoate or olazax or zalasta or zyprexa or zypadhera).tw,kf. 25 Triazolam/ or (1hm943223r or "28911-01-5 (triazolam)" or apo triazo or apo-triazo or halcion or triazolam or trilam or u 33,030 or u-33,030 or u33,030).tw,kf. 26 Amitriptyline/ or amitriptylin*.tw,kf. 27 Eszopiclone/ or (138729-47-2 or estorra or eszopiclone or lunesta or uzx80k71oe).tw,kf. 28 Flurazepam/ or ("1172-18-5 (di-hcl)" or "121531-42-8 (mono-perchlorate)" or "17617-23-1 (flurazepam)" or "36105-20-1 (mono-hcl)" or 756rdm536m or 7c4jh842ij or dalmadorm or dalmane or dormodor or flurazepam or ihp475989u or monohydrochloride, flurazepam or staurodorm).tw,kf. 29 Nitrazepam/ or ("146-22-5 (nitrazepam)" or 9clv70w7hs or alodorm or dormalon or dormo-puren or eatan or imadorm or imeson or mogadon or nitrazadon or nitrazep or nitrazepam or nitrodiazepam or novanox or radedorm or remnos or rhoxal nitrazepam or rhoxal-nitrazepam or serenade or somnite).tw,kf. 30 Zolazepam/ or (45sj093q1n or ci 716 or ci-716 or ci716 or flupyrazapon or flupyrazopon or g1r474u58u or zolazepam or zolazepam).tw,kf. 31 Zolpidem/ or (7k383oqi23 or ambien or amsic or bikalm or dalparan or "imidazo(1,2-a)pyridine-3-acetamide, n,n,6-trimethyl-2-(4-methylphenyl)-" or "n,n,6-trimethyl-2-(4-methylphenyl)imidazo(1,2a)pyridine-3-acetamide hemitartrate" or edluar or intermezzo or ivadal or sublinox or stilnoct or stilnox or tovalt or wy6w63843k or zodormdura or zoldem or zolirin or zolpi lich or zolpi-lich or zolpidem or zolpimist or zolpinox).tw,kf. 32 (BZA* or BZRA* or abecarnil or adinazolam or (adinazolam adj3 mesilate) or (alpha adj3 hydroxymidazolam) or alpidem or alprazolam or (amitriptyline adj3 chlordiazepoxide) or alapryl or arfendazam or bretazenil or bromazepam or brotizolam or camazepam or carburazepam or chlorazepam or chlordiazepoxide or (chlordiazepoxide adj3 clidinium bromide) or cinazepam or cinolazepam or clazolam or clobazam or clorazepate or (clorazepate adj3 dipotassium) or (clorazepate adj3 potassium) or clotiazepam or cloxazolam or coreminal or dealkylflurazepam or delorazepam or demoxepam or divaplon or doxans or doxefazepam or elavil or emapunil or estazolam or (ethyl adj3 loflazepate) or fasiplon or fludiazepam or flutoprazepam or flutazolam or gedocarnil or gidazepam or halazepam or haloxazolam or hidazepam or hydazepam or imidazenil or isoquinazepon or ketazolam or levana or lirequinil or lofendazam or loflazepate or loprazolam or (loprazolam adj3 mesilate) or lormetazepam or lorzem or medazepam or metaclazepam or mexazolam or midazolam or (midazolam adj3 maleate) or "n allyl 4 amino 1 (3 pentynyl) 1h pyrazolo[3,4 b]pyridine 5 carboxamide" or necopidem or nimetazepam or nitrazepate or norchlordiazepoxide or norclobazam or nordazepam or oxazepam or pagoclone or paxipam or persumbran or phenazepam or pinazepam or prazepam or premazepam or quazepam or remimazolam or "ro 23 0364" or saripidem or suproclone or suriclone or taniplon or temazepam or tetrazepam or tofisopam or triazolam or triflubazam or tuclazepam or uldazepam or uxepam or zaleplon or zapizolam or zolpidem tartrate or zopiclone).tw,kf. 33 or/1-32 [Benzodiazepine and Benzodiazepine Receptor Agonist Concept] 34 Anxiety/ or (angst or anxiet* or anxio* or dread or hypervigilance or hyper vigilance or nervous* or worry or worried or worriesome).tw,kf. 35 Anxiety Disorders/ 36 Agoraphobia/ or Fear/ or Phobic Disorders/ or Phobia, Social/ or (acrophobi* or aerophobi* or agoraphobi* or arachnophobi* or aviophobi* or basophobi* or claustrophobi* or fear* or mysophobi* or phobia* or phobic* or sociophobi* or thanatophobi* or zoophobi*).tw,kf. 37 Obsessive-Compulsive Disorder/ or ((anankastic adj3 personalit*) or (preoccup* adj3 neuros*) or obsessi* or compuls* or OCD).tw,kf. 38 Panic Disorder/ or Panic/ or (((panic adj3 attack*) or panic) adj3 disorder*).tw,kf. 39 Depression/ or depress*.tw,kf. 40 Depressive Disorder/ or melancholia*.tw,kf. 41 Depressive Disorder, Major/ or (involutional paraphrenia* or involutional psychos*).tw,kf. 42 Depressive Disorder, Treatment-Resistant/ 43 Stress Disorders, Post-Traumatic/ or (flashback* or flash back* or moral injur* or ptsd or post-traumatic neuros* or posttraumatic neuros* or posttraumatic psychos* or post traumatic psychos*or posttraumatic stress* or post traumatic stress*).tw,kf. 44 stress disorders, traumatic/ or combat disorders/ or exp psychological trauma/ or stress disorders, traumatic, acute/ 45 Stress Disorders, Traumatic, Acute/ or (acute stress adj3 disorder*).tw,kf. 46 Combat Disorders/ or ((combat adj3 disorder*) or combat neuros* or shell shock* or war neuros*).tw,kf. 47 Psychological Distress/ or (emotional distress* or emotional stress* or psychological distress*).tw,kf. 48 Sleep Initiation and Maintenance Disorders/ or (dyssomni* or "disorders of initiating and maintaining sleep*" or early awakening* or insomnia* or hyposomni* or nighttime awakening* or night time awakening* or nocturnal awakening or sleeplessness or (sleep* adj5 (debt* or deficit* or disorder* or dysfunction* or disturb* or fragment* loss*))).tw,kf. 49 or/34-48 [Anxiety, Depression or Insomnia Concept] 50 Deprescriptions/ or (deprescri* or de prescri*).tw,kf. 51 Overtreatment/ or (overtreatment* or therapeutic overus* or therapy overus* or unnecessary medical treatment* or unnecessary treatment*).tw,kf. 52 PolyPharmacy/ or (polypharmac* or poly pharmac* or polymedicat* or poly medicat* or polypragmas* or poly pragmas* or polypharmacoth* or poly pharmacoth).tw,kf. 53 Medication Errors/ or (erroneous prescri* or faulty prescr* or flawed prescri* or inappropriate prescri* or medication error* or misprescri* or misprescri* or prescribe* fault or prescrip* error or unsuitable prescribe* or wrong prescribi*).tw,kf. 54 Inappropriate Prescribing/ or (inappropriate multiple medicat* or inappropriate multiple prescrib* or inappropriate polymedicat* or unnecessary multiple drug treatment*).tw,kf. 55 ((ceas* or cessation or discontinu* or eliminat* or inappropriat* or minimi* or reduc* or stop* or taper* or withdraw* or withhold*) adj5 (prescrib* or prescription* or drug* or medication* or multidrug* or multi drug* or multipharm* or multi pharm* or polymedicat* or poly medicat* or overtreat* or over treat* or polypharm* or poly pharm* or polyprag* or poly prag*)).tw,kf. 56 or/50-55 [Deprescription Concept] 57 exp clinical pathway/ 58 exp clinical protocol/ 59 clinical protocols/ 60 exp consensus/ 61 exp consensus development conference/ 62 exp consensus development conferences as topic/ 63 critical pathways/ 64 exp guideline/ 65 guidelines as topic/ 66 exp practice guideline/ 67 practice guidelines as topic/ 68 health planning guidelines/ 69 Clinical Decision Rules/ 70 (guideline or practice guideline or consensus development conference or consensus development conference, NIH).pt. 71 (position statement* or policy statement* or practice parameter* or best practice*).ti,ab,kf. 72 (standards or guideline or guidelines).ti,kf. 73 ((practice or treatment* or clinical) adj guideline*).ab. 74 (CPG or CPGs).ti. 75 consensus*.ti,kf. 76 consensus*.ab. /freq=2 77 ((critical or clinical or practice) adj2 (path or paths or pathway or pathways or protocol*)).ti,ab,kf. 78 recommendat*.ti,kf. or guideline recommendation*.ab. 79 (care adj2 (standard or path or paths or pathway or pathways or map or maps or plan or plans)).ti,ab,kf. 80 (algorithm* adj2 (screening or examination or test or tested or testing or assessment* or diagnosis or diagnoses or diagnosed or diagnosing)).ti,ab,kf. 81 (algorithm* adj2 (pharmacotherap* or chemotherap* or chemotreatment* or therap* or treatment* or intervention*)).ti,ab,kf. 82 (guideline* or standards or consensus* or recommendat*).au. 83 (guideline* or standards or consensus* or recommendat*).ca. 84 or/57-83 [Guidelines Concept] 85 33 and 49 and 84 [Benzodiazepine | Anxiety and Depression | CPG] 86 33 and 56 and 84 [Benzodiazepine | Deprescribing | CPG] 87 86 use medall 88 85 use medall 89 87 or 88 [Medline Records] 90 exp benzodiazepine derivative/ or (12794-10-4 or benzodiazepin* or m0q7802g2b).tw,kf. 91 alprazolam/ or ("28981-97-7 (alprazolam)" or alprazolam or alprazolan or alprox or apo alpraz or apo-alpraz or cassadan or d-65mt or d65mt or esparon or kalma or niravam or novo alprazol or novo-alprazol or nu alpraz or nu-alpraz or ralozam or tafil or trankimazin or u-31,889 or u31,889 or xanax or yu55mq3izy).tw,kf. 92 benzodiazepinon*.tw,kf. 93 anthramycin/ or (0wzd9y66wn or "35599-87-2 ((11a alpha)-isomer)" or "4803-27-4 (anthramycin)" or anthramycin* or "anthramycin, (11a alpha)-isomer" or antramycin*).tw,kf. 94 bromazepam/ or ("1812-30-2 (bromazepam)" or anxyrex or bromalich or bromaz* or durazanil or lectopam or lexatin or lexomil or lexotan or lexotanil or ro 5-3350 or ro 53350 or x015l14v0o).tw,kf. 95 clonazepam/ or ("1622-61-3 (clonazepam)" or "2h-1,4-benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-" or 5pe9fde8gb or antelepsin or clonazepam* or klonopin or rivotril or ro 5-4023 or ro 54023).tw,kf. 96 devazepide/ or ("103420-77-5 (devazepide)" or devazepide* or je6p7qy7nh or l 364,718 or l-364,718 or l364,718 or mk 329 or mk-329 or mk329).tw,kf. 97 diazepam/ or ("439-14-5 (diazepam)" or 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one or apaurin or diazemuls or diazepam or diastat or faustan or q3jtx2q7tu or relanium or seduxen or sibazon or stesolid or valium).tw,kf. 98 nordazepam/ or ("1088-11-5 (nordazepam)" or 67220mcm01 or calmday or dealkylprazepam or demethyldiazepam or deoxydemoxepam or desmethyldiazepam or n desalkylhalazepam or n descyclopropylmethyl prazepam or n descyclopropylmethylprazepam or n destrifluoroethylhalazepam or n-desalkylhalazepam or n-descyclopropylmethyl-prazepam or n-descyclopropylmethylprazepam or n-destrifluoroethylhalazepam or nordaz or nordazepam or nordiazepam or norprazepam or ro 5 2180 or ro 5-2180 or ro 52180 or tranxilium n or vegesan).tw,kf. 99 flumazenil/ or (40p7xk9392 or "78755-81-4 (flumazenil)" or anexate or flumazenil or flumazepil or lanexat or ro 15 1788 or ro 15-1788 or ro 151788 or romazicon).tw,kf. 100 flunitrazepam/ or ("1622-62-4 (flunitrazepam)" or 620x0222fq or fluni 1a pharma or flunibeta or flunimerck or fluninoc or flunitrazepam or flunizep von ct or fluridrazepam or narcozep or ro-5-4200 or ro54200 or rohipnol or rohypnol or von ct, flunizep).tw,kf. 101 flurazepam/ or ("1172-18-5 (di-hcl)" or "121531-42-8 (mono-perchlorate)" or "17617-23-1 (flurazepam)" or "36105-20-1 (mono-hcl)" or 756rdm536m or 7c4jh842ij or dalmadorm or dalmane or dormodor or flurazepam or ihp475989u or somnol or staurodorm).tw,kf. 102 lorazepam/ or ("846-49-1 (lorazepam)" or ativan or donix or duralozam or durazolam or idalprem or laubeel or lorazep von ct or lorazepam* or loreev or novo lorazem or novolorazem or nu loraz or nu-loraz or o26fzp769l or orfidal wyeth or sedicepan or sinestron or somagerol or temesta or tolid or von ct, lorazep or wy 4036 or wy-4036 or wy4036 or wyeth, orfidal).tw,kf. 103 oxazepam/ or ("604-75-1 (oxazepam)" or 6gow6dwn2a or adumbran or oxpam or oxazepam or serax or tazepam).tw,kf. 104 pirenzepine/ or (10ym403fls or 3g0285n20n or gastrotsepin or gastrozepin or l-s 519 or ls 519 or ls-519 or ls519 or piren basan or piren-basan or pirenzepin* or pyrenzepine or ulcoprotect or ulgescum).tw,kf. 105 prazepam/ or ("2955-38-6 (prazepam)" or centrax or demetrin or lysanxia or mono demetrin or prazepam or q30vcc064m or reapam or sedapran or trepidan).tw,kf. 106 temazepam/ or (3 hydroxydiazepam or 3-hydroxydiazepam or "846-50-4 (temazepam)" or chb1qd2qss or corax or dasuen or euhypnos or hydroxydiazepam or levanxol or medilium or methyloxazepam or nocturne or norkotral tema or normison or normitab or nortem or oxydiazepam or planum or pronervon t or remestan or restoril or ro 5 5345 or ro-5-5345 or ro55345 or sah 47 603 or sah 47-603 or sah 47603 or signopam or tema, norkotral or temaze or temazep von ct or temazepam or temtabs or tenox or von ct, temazep or wy 3917 or wy-3917 or wy3917).tw,kf. 107 chlordiazepoxide/ or ("121531-47-3 (mono-hclo4)" or "14844-23-6 (hcl)" or "438-41-5 (mono-hcl)" or "56617-98-2 (hbr)" or "58-25-3 (chlordiazepoxide)" or 6rz6xez3cr or 7 chloro 2 methylamino 5 phenyl 3h 1,4 benzodiazepine 4 oxide or 7 chloro n methyl 5 phenyl 3h 1,4 benzodiazepin 2 amine 4 oxide or 7-chloro-2-methylamino-5-phenyl-3h-1,4-benzodiazepine-4-oxide or 7-chloro-n-methyl-5-phenyl-3h-1,4-benzodiazepin-2-amine 4-oxide or chlordiazepoxide or chlozepid or elenium or librium or mfm6k1xwdk or methaminodiazepoxide).tw,kf. 108 clobazam/ or (1-phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3h-1,5-benzodiazepine or "22316-47-8 (clobazam)" or 2mro291b4u or clobazam or frisium or hr 376 or lm 2717 or lm-2717 or lm2717 or onfi or urbanyl).tw,kf. 109 clorazepate dipotassium/ or (4306-cb or "57109-90-7 (clorazepate dipotassium)" or 63fn7g03xy or chlorazepate or clorazepate or clorazepic acid or d51wo0g0l4 or dipotassium chlorazepate or ms63g8nqui or tranxene or tranxilium).tw,kf. 110 estazolam/ or ("29975-16-4 (estazolam)" or 36s3eqv54c or d-40ta or d40ta or estazolam or nuctalon or prosom or tasedan).tw,kf. 111 medazepam/ or ("2898-11-5 (mono-hcl)" or "2898-12-6 (medazepam)" or etm878jc9k or medazepam or nobrium or p0j3387w3s or ro 5 4556 or ro 5-4556 or ro 54556 or rudotel or rusedal).tw,kf. 112 midazolam/ or (77520s18se or dormicum or midazolam or r60l0sm5bc or ro 21 3981 or ro 21-3981 or ro 213981 or versed or w7ttw573jj).tw,kf. 113 olanzapine/ or ("2-methyl-4-(4-methyl-1-piperazinyl)-10h-thieno(2,3-b)(1,5)benzodiazepine" or olanzapine pamoate or olazax or zalasta or zyprexa or zypadhera).tw,kf. 114 triazolam/ or (1hm943223r or "28911-01-5 (triazolam)" or apo triazo or apo-triazo or halcion or triazolam or trilam or u 33,030 or u-33,030 or u33,030).tw,kf. 115 amitriptyline/ or amitriptylin*.tw,kf. 116 eszopiclone/ or (138729-47-2 or estorra or eszopiclone or lunesta or uzx80k71oe).tw,kf. 117 flurazepam/ or ("1172-18-5 (di-hcl)" or "121531-42-8 (mono-perchlorate)" or "17617-23-1 (flurazepam)" or "36105-20-1 (mono-hcl)" or 756rdm536m or 7c4jh842ij or dalmadorm or dalmane or dormodor or flurazepam or ihp475989u or monohydrochloride, flurazepam or staurodorm).tw,kf. 118 nitrazepam/ or ("146-22-5 (nitrazepam)" or 9clv70w7hs or alodorm or dormalon or dormo-puren or eatan or imadorm or imeson or mogadon or nitrazadon or nitrazep or nitrazepam or nitrodiazepam or novanox or radedorm or remnos or rhoxal nitrazepam or rhoxal-nitrazepam or serenade or somnite).tw,kf. 119 zolazepam/ or (45sj093q1n or ci 716 or ci-716 or ci716 or flupyrazapon or flupyrazopon or g1r474u58u or zolazepam or zolazepam).tw,kf. 120 zolpidem/ or (7k383oqi23 or ambien or amsic or bikalm or dalparan or "imidazo(1,2-a)pyridine-3-acetamide, n,n,6-trimethyl-2-(4-methylphenyl)-" or "n,n,6-trimethyl-2-(4-methylphenyl)imidazo(1,2a)pyridine-3-acetamide hemitartrate" or edluar or intermezzo or ivadal or sublinox or stilnoct or stilnox or tovalt or wy6w63843k or zodormdura or zoldem or zolirin or zolpi lich or zolpi-lich or zolpidem or zolpimist or zolpinox).tw,kf. 121 adinazolam/ or adinazolam.tw,kf. 122 abecarnil/ or abecarnil.tw,kf. 123 adinazolam mesilate/ or ((adinazolam adj3 mesylate) or (adinazolam adj3 mesilate) or deracyn).tw,kf. 124 alpha hydroxymidazolam/ or (alpha adj3 hydroxymidazolam).tw,kf. 125 alpidem/ or (alpidem* or Ananxyl).tw,kf. 126 arfendazam/ or arfendazam.tw,kf. 127 bretazenil/ or bretazenil.tw,kf. 128 brotizolam/ or (brotizolam or dormex or ladormin or lendorm or lendormin or lindormin or mederantil or sintonal or we 941).tw,kf. 129 camazepam/ or (albego or camazepam or paxor).tw,kf. 130 chlorazepam/ or (chloral hydrate plus diazepam or diazepam plus chloral hydrate).tw,kf. 131 cinolazepam/ or gerodorm ox 373.tw,kf. 132 clotiazepam/ or (clozan or distensan or rize tor recalmo).tw,kf. 133 cloxazolam/ or (enadel or lubalix or olcadil or olquadil or sepazon).tw,kf. 134 dealkylflurazepam/ or (Desalkylflurazepam or dideethylflurazepam or didesethylflurazepam or flurazepam dealkyl or norflurazepam).tw,kf. 135 delorazepam/ or (chlordemethyldiazepam or chlordesmethyldiazepam or chloro n demethyldiazepam or chlorodemethyldiazepam or chlorodesmethyldiazepam or chloronordiazepam).tw,kf. 136 demoxepam/ or (chlordiazepoxide lactam or demethyldiazepam oxide or demoxepan or nordiazepam oxide or nsc 46077 or ro 5 2092).tw,kf. 137 divaplon/ or (divaplon or ru 32698 or ru32698).tw,kf. 138 doxefazepam/ or (doxefazepam or doxans).tw,kf. 139 emapunil/ or emapunil.tw,kf. 140 fasiplon/ or fasiplon.tw,kf. 141 fludiazepam/ or (fludiazepam or erispan).tw,kf. 142 flutoprazepam/ or (flutoprazepam or restas).tw,kf. 143 gedocarnil/ or gedocarnil.tw,kf. 144 gidazepam/ or gidazepam.tw,kf. 145 halazepam/ or (halazepam or alapryl or pacinone or paxipam or sch 12041).tw,kf. 146 haloxazolam/ or (haloxazolam or cs 430 or cs430 or somelin).tw,kf. 147 imidazenil/ or imidazenil.tw,kf. 148 ketazolam/ or (anseren or ketazolam or anxon or contamexor solatran or unacalm or unakalm).tw,kf. 149 loflazepate/ or (loflazepate or cm 6913 or cm6913).tw,kf. 150 loprazolam/ or (loprazolam or hr 158 or hr 31158 or hr158 or hr31158 or ru 31158 or ru31158 or triazulenone).tw,kf. 151 lormetazepam/ or (lormetazepam or ch 757 or ch757 or ergocalm or loramet or loranka or loretam or methyllorazepam or minians or minias or noctamid or noctamide or pronoctan or ro 5 5516 or ro 55516 or ro55516 or sedalam or sedalor or wy 4082 or wy4082).tw,kf. 152 medazepam/ or (medazepam or anxitol or diepin or mezepam nobrium or rb 252 or resmit or "ro 05 4556" or ro 5 4556 or ro 54556 or rudotel or s 804 or siman).tw,kf. 153 metaclazepam/ or (metaclazepam or brometazepamor ka 2547 or ka2547 or kc 2547 or kc2547 or metuclazepamor talis).tw,kf. 154 mexazolam/ or (mexazolam orcs 386or cs386 or melex).tw,kf. 155 necopidem/ or necopidem.tw,kf. 156 nimetazepam/ or (nimetazepam orerimin or hypnon or s 1530 or s1530).tw,kf. 157 norchlordiazepoxide/ or (norchlordiazepoxide or demethylchlordiazepoxide or demethylchlorodiazepoxide or desmethylchlordiazepoxide).tw,kf. 158 norclobazam/ or (norclobazam or demethylclobazam or desmethylclobazamor).tw,kf. 159 pagoclone/ or (pagoclone or ci 1043 or ci1043 or ip 456 or ip456 or rp 59037 or rp 62955 or rp59037 or rp62955).tw,kf. 160 persumbran/ or (persumbran or persumbrax).tw,kf. 161 phenazepam/ or (phenazepam or fenazepam or phenasepam).tw,kf. 162 pinazepam/ or (pinazepam or domar).tw,kf. 163 premazepam.mp. or premazepam.tw,kf. [mp=ti, ab, hw, tn, ot, dm, mf, dv, kf, fx, dq, bt, nm, ox, px, rx, ui, sy] 164 quazepam/ or (quazepam or doral or dormalin or oniria or prosedar or quazium or sch 161 or sch 16134 or sch161 or sch16134 or selepam).tw,kf. 165 remimazolam/ or (remimazolam oranerem or biprazine pf or byfavo or cns 7056 or cns 7056b or cns7056 or cns7056b or gw 502056x or gw502056x or hr 7056 or hr7056 or ono 2745 or ono 2745bs or ono in251 or ono2745 or ono2745bs or onoin251 or rf 10007 or rf10007 or ruima).tw,kf. 166 saripidem/ or saripidem.tw,kf. 167 suproclone/ or suproclone.tw,kf. 168 suriclone/ or (rp 31264 or suril or suriclone or zuriclone).tw,kf. 169 tetrazepam/ or (tetrazepam ormusapam or musaril or myolastam or myolastan or myolastin or myospasmal or spasmorelax or tetra saar or tetramdura or tetrasaar).tw,kf. 170 tofisopam/ or (tofisopam or dextofisopamor grandaxin or levotofisopam or seriel or tofizopam).tw,kf. 171 uxepam/ or uxepam.tw,kf. 172 zaleplon/ or (zaleplon or andante or cl 284846 or cl284846 or hegon or hipnodem or l 846 or l846 or ljc 10846 or ljc10846 or noctiplon or plenidon or sonata or starnocor zaplon or zerene).tw,kf. 173 zapizolam/ or zapizolam.tw,kf. 174 zolpidem tartrate/ or (zolpidem tartrate or adormix or ambien or ambien cr or amsic or bikalm or durnit or edluar or intermezzo or myslee or niotal or nitrest or somit or somnil or somno or stilnix or stilnoct or stilnox or stilpidem or supedal or tovalt odt or ziohex or zodorm or zolpimist or zolpinox or zopidem or zopim).tw,kf. 175 zopiclone/ or (zopiclone oramoban or imovance or imovane or rp 27267 or rp27267 or ximovan or zimovane or zopic or zoplicon).tw,kf. 176 (BZA* or BZRA* or (amitriptyline adj3 chlordiazepoxide) or alapryl or bromazepam or brotizolam or carburazepam or cinazepam or clazolam or cloxazolam or coreminal or elavil or (ethyl adj3 loflazepate) or flutazolam or hidazepam or hydazepam or isoquinazepon or levana or lirequinil or lofendazam or mexazolam or nitrazepate or norchlordiazepoxide or premazepam or quazepam or remimazolam or "ro 23 0364" or taniplon or triflubazam or tuclazepam or uldazepam).tw,kf. 177 or/90-176 [Benzodiazepine and Benzodiazepine Receptor Agonist Concept] 178 anxiety/ or (angst or anxiet* or anxio* or dread or hypervigilance or hyper vigilance or nervous* or worry or worried or worriesome).tw,kf. 179 anxiety disorder/ 180 phobia/ or acrophobia/ or agoraphobia/ or exp animal phobia/ or claustrophobia/ or flying phobia/ or social phobia/ 181 phobia/ or acrophobia/ or agoraphobia/ or exp animal phobia/ or claustrophobia/ or flying phobia/ or social phobia/ or fear/ or (acrophobi* or aerophobi* or agoraphobi* or arachnophobi* or aviophobi* or basophobi* or claustrophobi* or fear* or mysophobi* or phobia* or phobic* or sociophobi* or thanatophobi* or zoophobi*).tw,kf. 182 obsessive compulsive disorder/ or obsession/ or ((anankastic adj3 personalit*) or (preoccup* adj3 neuros*) or obsessi* or compuls* or OCD).tw,kf. 183 panic/ or (((panic adj3 attack*) or panic) adj3 disorder*).tw,kf. 184 depression/ or chronic depression/ or depressive psychosis/ or major depression/ or melancholia*.tw,kf. 185 depression/ or chronic depression/ or depressive psychosis/ or major depression/ or (melancholia* or involutional paraphrenia* or involutional psychos*).tw,kf. 186 treatment resistant depression/ 187 posttraumatic stress disorder/ or (flashback* or flash back* or moral injur* or ptsd or post-traumatic neuros* or posttraumatic neuros* or posttraumatic psychos* or post traumatic psychos*or posttraumatic stress* or post traumatic stress*).tw,kf. 188 combat stress/ or psychotrauma/ or acute stress disorder/ 189 combat stress/ or psychotrauma/ or acute stress disorder/ or ((acute stress adj3 disorder*) or (combat adj3 disorder*) or combat neuros* or shell shock* or war neuros*).tw,kf. 190 distress syndrome/ or (emotional distress* or emotional stress* or psychological distress*).tw,kf. 191 sleep disorder/ or exp insomnia/ or nocturnal awakening/ or exp sleep disordered breathing/ or (dyssomni* or "disorders of initiating and maintaining sleep*" or early awakening* or insomnia* or hyposomni* or nighttime awakening* or night time awakening* or nocturnal awakening or sleeplessness or (sleep* adj5 (debt* or deficit* or disorder* or dysfunction* or disturb* or fragment* loss*))).tw,kf. 192 or/178-191 [Anxiety, Depression or Insomnia Concept] 193 deprescription/ or (deprescri* or de prescri*).tw,kf. 194 overtreatment/ or inappropriate polypharmacy/ or (overtreatment* or therapeutic overus* or therapy overus* or unnecessary medical treatment* or unnecessary treatment*).tw,kf. 195 polypharmacy/ or (polypharmac* or poly pharmac* or polymedicat* or poly medicat* or polypragmas* or poly pragmas* or polypharmacoth* or poly pharmacoth).tw,kf. 196 medication error/ or (erroneous prescri* or faulty prescr* or flawed prescri* or inappropriate prescri* or medication error* or misprescri* or misprescri* or prescribe* fault or prescrip* error or unsuitable prescribe* or wrong prescribi*).tw,kf. 197 prescribing error/ or exp unnecessary prescribing/ or (inappropriate multiple medicat* or inappropriate multiple prescrib* or inappropriate polymedicat* or unnecessary multiple drug treatment*).tw,kf. 198 ((ceas* or cessation or discontinu* or eliminat* or inappropriat* or minimi* or reduc* or stop* or taper* or withdraw* or withhold*) adj5 (prescrib* or prescription* or drug* or medication* or multidrug* or multi drug* or multipharm* or multi pharm* or polymedicat* or poly medicat* or overtreat* or over treat* or polypharm* or poly pharm* or polyprag* or poly prag*)).tw,kf. 199 or/193-198 [Deprescription Concept] 200 (guideline or practice guideline or consensus development conference or consensus development conference, NIH).pt. 201 (guideline* or standards or consensus* or recommendat*).ti. 202 (practice parameter* or position statement* or policy statement* or CPG or CPGs or best practice*).ti. 203 (care adj2 (path or paths or pathway or pathways or map or maps or plan or plans or standard)).ti. 204 ((critical or clinical or practice) adj2 (path or paths or pathway or pathways or protocol*)).ti. 205 (algorithm* and (pharmacotherap* or chemotherap* or chemotreatment* or therap* or treatment* or intervention*)).ti. 206 (algorithm* and (screening or examination or test or tested or testing or assessment* or diagnosis or diagnoses or diagnosed or diagnosing)).ti. 207 (guideline* or standards or consensus* or recommendat*).au. 208 (guideline* or standards or consensus* or recommendat*).co. 209 (guideline* or standards or consensus* or recommendat*).ca. 210 systematic review.ti,pt,kf,sh. and (practice guideline* or treatment guideline* or clinical guideline* or guideline recommendation*).ti,ab,kf. 211 or/200-210 [CADTH Standard Guideline Filter] 212 177 and 192 and 211 [Benzodiazepine | Anxiety and Depression | CPG] 213 177 and 199 and 211 [Benzodiazepine | Deprescribing | CPG] 214 212 use oemezd 215 213 use oemezd 216 214 or 214 [Embase Results] 217 89 or 216 [Medline or Embase Records] 218 remove duplicates from 217 |