Dr. Paul Pavlidis Dataverse
Featured Dataverses

In order to use this feature you must have at least one published dataverse.

Publish Dataverse

Are you sure you want to publish your dataverse? Once you do so it must remain published.

Publish Dataverse

This dataverse cannot be published because the dataverse it is in has not been published.

Delete Dataverse

Are you sure you want to delete your dataverse? You cannot undelete this dataverse.

Advanced Search

1 to 10 of 37 Results
Mar 6, 2023
Morin, Alexander, 2022, "Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets", https://doi.org/10.5683/SP3/MAFGFL, Borealis, V2, UNF:6:NWNf4+NelyKPsz/pxyKZ2A== [fileUNF]
There is a growing collection of genomics data sets generated for identifying the gene targets under control of transcription regulators (TRs). TR ChIP-seq and RNA expression experiments that perturb TR activity are the most common strategies for mapping TRs to genes at a genomic...
Apr 13, 2021
Chu, Eric Ching-Pan, 2021, "Experiment level curation identifies high confidence transcriptional regulatory interactions in neurodevelopment", https://doi.org/10.5683/SP2/XLLWRL, Borealis, V2, UNF:6:iXXMqIoqZ232Qn5IPlsGWg== [fileUNF]
The capacity to computationally reconstruct gene regulatory networks using large-scale biological data is currently limited by the absence of a high confidence set of one-to-one regulatory interactions. Given the lengthy history of using small scale experimental assays to investi...
Mar 4, 2020
Kathryn L. Post; Manuel Belmadani; Payel Ganguly; Fabian Meili; Riki Dingwall; Troy A. McDiarmid; Warren M. Meyers; Caitlin Herrington; Barry P. Young; Daniel B. Callaghan; Sanja Rogic; Matthew Edwards; Ana Niciforovic; Alessandro Cau; Catharine H. Rankin; Timothy P. O’Connor; Shernaz X. Bamji; Christopher J. Loewen; Douglas W. Allan; Paul Pavlidis; Kurt Haas, 2020, "Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction", https://doi.org/10.5683/SP2/DQOKPB, Borealis, V1
Supporting data for "Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction"
Oct 31, 2019
McDiarmid, Troy A.; Belmadani, Manuel; Liang, Joseph; Mieli, Fabian; Mathews, Eleanor A.; Mullen, Gregory P.; Hendi, Ardalan; Wong, Wan-Rong; Rand, James B.; Mizumoto, Kota; Haas, Kurt; Pavlidis, Paul; Rankin, Catharine H., 2019, "Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation", https://doi.org/10.5683/SP2/FJWIL8, Borealis, V3
Supporting data for "Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation"
Apr 15, 2019
Rogic, Sanja, 2019, "Whole genome sequencing and variant discovery in the ASPIRE autism spectrum disorder cohort", https://doi.org/10.5683/SP2/2UILPN, Borealis, V2
Supplementary files for the manuscript submission
Mar 12, 2019
Rogic, Sanja; Pavlidis, Paul, 2019, "Meta-analysis of kindling-induced gene expression changes in the rat hippocampus", https://doi.org/10.5683/SP2/CFCJPY, Borealis, V1
Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies. Because this conclusion was based on retrospective compa...
Mar 12, 2019
Pavlidis, Paul; Noble, William S., 2019, "Analysis of strain and regional variation in gene expression in mouse brain", https://doi.org/10.5683/SP2/GPWPKX, Borealis, V1
BACKGROUND: We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains. In the previous analysis, 24 genes showing expression differences between the strains and about 240 genes with r...
Mar 12, 2019
Pavlidis, Paul, 2019, "Using ANOVA for gene selection from microarray studies of the nervous system", https://doi.org/10.5683/SP2/QCLEIJ, Borealis, V1
Methods are presented for detecting differential expression using statistical hypothesis testing methods including analysis of variance (ANOVA). Practicalities of experimental design, power, and sample size are discussed. Methods for multiple testing correction and their applicat...
Mar 12, 2019
Verbitsky, Miguel; Yonan, Amanda L.; Malleret, Gael; Kandel, Eric R; Gilliam, T. Conrad; Pavlidis, Paul, 2019, "Altered Hippocampal Transcript Profile Accompanies an Age-Related Spatial Memory Deficit in Mice", https://doi.org/10.5683/SP2/YTDEPN, Borealis, V1
We have carried out a global survey of age-related changes in mRNA levels in the C57BL/6NIA mouse hippocampus and found a difference in the hippocampal gene expression profile between 2-month-old young mice and 15-month-old middle-aged mice correlated with an age-related cognitiv...
Mar 12, 2019
Pavlidis, Paul; Li, Qinghong; Noble, William Stafford, 2019, "The effect of replication on gene expression microarray experiments", https://doi.org/10.5683/SP2/EYESM1, Borealis, V1
MOTIVATION: We examine the effect of replication on the detection of apparently differentially expressed genes in gene expression microarray experiments. Our analysis is based on a random sampling approach using real data sets from 16 published studies. We consider both the abili...
Add Data

Sign up or log in to create a dataverse or add a dataset.

Share Dataverse

Share this dataverse on your favorite social media networks.

Link Dataverse
Reset Modifications

Are you sure you want to reset the selected metadata fields? If you do this, any customizations (hidden, required, optional) you have done will no longer appear.