The Pediatric Sepsis Data CoLaboratory (Sepsis CoLab) is an international data-sharing network for collaboration to address pediatric sepsis mortality and morbidity. It is led by the Institute for Global Health (IGH) at BC Children’s Hospital and BC Women's Hospital + Health Centre, and the World Federation of Pediatric Intensive and Critical Care Societies (WFPICCS).

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1 to 10 of 78 Results
The epidemiology and risk factors for postnatal complications among postpartum women and neonates in Southwestern Uganda: a prospective cohort study
Aug 14, 2024 - Smart Discharges - Manuscripts
Pillay,Yashodani; Ngonzi, Joseph; Nguyen, Vuong; Payne, Beth A; Komugisha, Clare; Twinomujuni, Annet H.; Vidler, Marianne; Lavoie, Pascal M.; Bebell, Lisa M.; Christoffersen-Deb, Astrid; Kenya-Mugisha, Nathan; Kissoon, Niranjan; Ansermino, J Mark; Wiens, Matthew O., 2024, "The epidemiology and risk factors for postnatal complications among postpartum women and neonates in Southwestern Uganda: a prospective cohort study", https://doi.org/10.5683/SP3/4BUCSY, Borealis, V1
Background: Sub-Saharan Africa accounts for two-thirds of the global burden of maternal and newborn deaths. Adverse outcomes among postpartum women and newborns occurring in the first six weeks of life are often related, though data co-examining patients are limited. This study i...
Smart Discharges Program for children with sepsis in Uganda: a qualitative program evaluation
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Wiens, Matthew O.; Jacob, Shevin T.; Kabajaasi, Olive; Kenya Mugisha, Nathan, 2024, "Smart Discharges Program for children with sepsis in Uganda: a qualitative program evaluation", https://doi.org/10.5683/SP3/VAKMMD, Borealis, V1
Background: Pediatric sepsis continues to be a significant burden in low- and middle-income countries. Studies have shown that in-hospital mortality is equal to, and sometimes exceeds, mortality during the post-discharge period. These facts call for a concerted action to improve...
Smart Discharges for vulnerable refugee children: a cohort study to validate prognostic algorithms for post-discharge readmission and mortality among children living in refugee settings
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Wiens, Matthew O; Toliva,Opar Bernard; Nsungwa-Sabiiti, Jesca; Mwaka, Savio; Komugisha, Clare; Nyalwal, Beatrice Lydiah Adhiambo; Bone, Jeffrey; Nguyen, Vuong; Kenya-Mugisha, Nathan, 2024, "Smart Discharges for vulnerable refugee children: a cohort study to validate prognostic algorithms for post-discharge readmission and mortality among children living in refugee settings", https://doi.org/10.5683/SP3/KCFQ9U, Borealis, V1
Background: In many African countries, pediatric post-discharge mortality following in-hospital treatment for severe infectious illness is higher than in-hospital mortality (5-8%). Risk algorithms can be used to help health workers identify those most vulnerable to poor post-disc...
Smart Discharges to improve pediatric post-discharge survival
Jul 22, 2024 - Smart Discharges - Manuscripts
Wiens, Matthew O; Tagoola, Abner; Kissoon, Niranjan; Ansermino, J Mark; Oyella Sherine, Sheila; Byaruhanga, Emmanuel; Ssemwanga, Edwards; Zhang, Cherri; Nguyen, Vuong; Bone, Jeffery N; Kenya Mugisha, Nathan; Kumbakumba, Elias; Kabakyenga, Jerome, 2024, "Smart Discharges to improve pediatric post-discharge survival", https://doi.org/10.5683/SP3/BGSQKD, Borealis, V1
Background: In Sub-Saharan Africa, pediatric post-discharge death is increasingly recognized as an important contributor to mortality. Current studies evaluating interventional approaches for post-discharge mortality focus on pharmacologic therapy, though only malaria prophylaxis...
Smart Discharges to improve post-discharge health outcomes in children in Rwanda
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Umuhoza, Christian; Hooft, Anneka; Uwiragiye, Emmanuel; Kornblith, Aaron; Wiens, Matthew O, 2024, "Smart Discharges to improve post-discharge health outcomes in children in Rwanda", https://doi.org/10.5683/SP3/NTNTZX, Borealis, V1
Background: The Smart Discharges studies in Uganda have enrolled over 10,000 children under-five with sepsis and have shown that death after hospital discharge occurs in 5-8% of patients, which is as common as death during the primary admission. The Smart Discharges evidence-base...
Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda: A multicohort analysis
Jul 16, 2024 - Smart Discharges - Manuscripts
Wiens, Matthew O; Nguyen, Vuong; Bone, Jeffrey N; Kumbakumba, Elias; Businge, Stephen; Tagoola, Abner; Sherine, Sheila Oyella; Byaruhanga, Emmanuel; Ssemwanga, Edward; Barigye, Celestine; Nsungwa, Jesca; Olaro,Charles; Ansermino, J Mark; Kissoon, Niranjan; Singer, Joel; Larson, Charles P; Lavoie, Pascal M; Dunsmuir, Dustin; Moschovis, Peter P; Novakowski, Stefanie; Komugisha, Clare; Tayebwa, Mellon; Mwesigwa, Douglas; Knappett, Martina; West, Nicholas; Kenya-Mugisha, Nathan; Kabakyenga, Jerome, 2024, "Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda: A multicohort analysis", https://doi.org/10.5683/SP3/M3OPKQ, Borealis, V1
Background: In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed t...
Geographical validation of the Smart Triage Model by age group
Jun 13, 2024 - Smart Triage - Manuscripts
Zhang, Cherri; Wiens, Matthew O; Dunsmuir, Dustin; Pillay, Yashodani; Huxford, Charly; Kimutai, David; Tenywa, Emmanuel; Ouma, Mary; Kigo, Joyce; Kamau, Stephen; Chege, Mary; Kenya-Mugisha, Nathan; Mwaka, Savio; Dumont, Guy A; Kisson, Niranjan; Akech, Samuel; Ansermino, J Mark, 2024, "Geographical validation of the Smart Triage Model by age group", https://doi.org/10.5683/SP3/4OI0BI, Borealis, V2
Background: Age is an important risk factor among critically ill children with neonates being the most vulnerable. Clinical prediction models need to account for age differences and must be externally validated and updated, if necessary, to enhance reliability, reproducibility, a...
Etiology of hospital mortality in children living in low-and middle-income countries: a systematic review and meta-analysis
Jun 12, 2024 - PALISI Global Health - Manuscripts
Kortz, Teresa B; Mediratta, Rishi; Smith, Audrey M; Nielsen, Katie R; Agulnik, Asya; Gordon Rivera, Stephanie; Reeves, Hailey; O'Brien, Nicole F; Hau Lee, Jan; Abbas, Qalab; Attebery, Jonah E; Bacha, Tigist; Bhutta, Emaan G; Biewen, Carter; Camacho-Cruz, Jhon; Munoz, Alvaro Coronado; DeAlmeida, Mary L; Domeryo Owusu, Larko; Fonseca, Yudy; Hooli, Shubhada; Johnson, Hunter C; Leimanis-Laurens, Mara; Mally, Deogratisu Nicholaus; McCarthy, Amanda M; Mutekanga, Andrew; Pineda, Carol; Remy, Kenneth E; Sanders, Sara C.; Tabor, Erica; Rodrigues Teixeira, Adriana; Qi Jyuee Want, Justin; Kissoon, Niranjan; Takwoingi, Yemisi; Wiens, Matthew O; Bhutta, Adnan, 2024, "Etiology of hospital mortality in children living in low-and middle-income countries: a systematic review and meta-analysis", https://doi.org/10.5683/SP3/2UKUKW, Borealis, V1, UNF:6:aiph6Iuwi9m6OKCXhI/QUQ== [fileUNF]
Background: In 2019, 80% of the 7.4 million global child deaths occurred in low- and middle-income countries (LMICs). Global and regional estimates of cause of hospital death and admission in LMIC children are needed to guide global and local priority setting and resource allocat...
PALISI Global Health - Manuscripts(University of British Columbia)
Jun 12, 2024PALISI - Global Health
PALISI - Global Health(University of British Columbia)
Jun 12, 2024PALISI
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