The rhythmic contractions of the gut are paced by the interstitial cells of Cajal (ICC). A network of ICC cover the length of the gut. Each ICC generates an electrical oscillation and these oscillations are synchronized into electrical waves ("slow waves") which travel the length of the gut and cause the muscle to contract. Synchronisation can be described mathematically by the theory of coupled oscillators. This dataverse contains data related to publications from the lab of Jan Huizinga at McMaster University on the coupled oscillator mechanism in the small intestine.
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Regular contractions over a period of two hours.
Regular contractions over a period of two hours.
Nov 18, 2019
Parsons, Sean, 2019, "Regular contractions over a period of two hours.", https://doi.org/10.5683/SP2/QMJHNL, Borealis, V1
Near-consecutive DMaps of a small intestine (start times indicated at left) over a period of almost two hours. Note that at 10:46 (the start of the first map) the intestine had already been over 40 minutes in the organ bath and 1.5 hours had elapsed since it was removed from the...
Two-chain FHN model
Nov 4, 2019
Parsons, Sean, 2019, "Two-chain FHN model", https://doi.org/10.5683/SP2/8LJ8UU, Borealis, V1
The MATLAB code for the two-chain Fitzhugh-Nagumo oscillator model. The main file to run is FHN_2Layer_run.m
Contraction and distension during stripes
Oct 11, 2019
Parsons, Sean, 2019, "Contraction and distension during stripes", https://doi.org/10.5683/SP2/A7RJKX, Borealis, V1
Left, simultaneous video from two cameras of the same small intestine, corresponding to the two boxed sections of the DMap in Figure 5. Right, corresponding DMaps: the moving green line indicates the temporal position in the video. Vertical green scale bars are 1 cm and horizonta...
Strain waves: DMap to Imap animations
Strain waves: DMap to Imap animations
Aug 8, 2017
Parsons, Sean, 2017, "Strain waves: DMap to Imap animations", https://doi.org/10.5683/SP/WP95DH, Borealis, V1
Strain waves are propagating changes in the interval between contraction waves in the small intestine, usually associated with a wave termination or dislocation. These GIF animations are interpolations between diameter maps (DMaps), which show contractions, and corresponding inte...
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