Data repository for papers published by the Winnik group
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Changing Surface Polyethylene Glycol Architecture Affects Elongated Nanoparticle Penetration into Multicellular Tumor Spheroids
Changing Surface Polyethylene Glycol Architecture Affects Elongated Nanoparticle Penetration into Multicellular Tumor Spheroids
Feb 28, 2022
Roberts, Megan G; Facca, Valerie J.; Keunen, Rachel; Yu, Qing; Reilly, Raymond M.; Winnik, Mitchell A., 2022, "Changing Surface Polyethylene Glycol Architecture Affects Elongated Nanoparticle Penetration into Multicellular Tumor Spheroids", https://doi.org/10.5683/SP3/MCCLHU, Borealis, V1, UNF:6:fem3AqeXfItDbui5WJ+7Hg== [fileUNF]
Modular nanoconjugates present opportunities to explore the interactions of anisotropic nanoparticles (NPs) in biological environments. To promote colloidal stability and biocompatibility, most NPs designed for biomedical applications are coated with polyethylene glycol (PEG) bru...
Biotinylated Lipid-Coated NaLnF4 Nanoparticles: Demonstrating the use of Lanthanide Nanoparticle-Based Reporters in Suspension and Imaging Mass Cytometry
Biotinylated Lipid-Coated NaLnF4 Nanoparticles: Demonstrating the use of Lanthanide Nanoparticle-Based Reporters in Suspension and Imaging Mass Cytometry
Feb 11, 2022
Arnett, Loryn P., 2022, "Biotinylated Lipid-Coated NaLnF4 Nanoparticles: Demonstrating the use of Lanthanide Nanoparticle-Based Reporters in Suspension and Imaging Mass Cytometry", https://doi.org/10.5683/SP3/V0PRLU, Borealis, V1
Lanthanide nanoparticles (LnNPs) have the potential to be used as high-sensitivity mass tag reporters in mass cytometry immunoassays. For this application, however, the LnNPs must be made colloidally stable in aqueous buffers, demonstrate minimal non-specific binding to cells, an...
Polymeric dipicolylamine based mass tags for mass cytometry
Feb 5, 2022
Zheng, Yefeng; Liu, Peng; Majonis, Daniel; Winnik, Mitchell A., 2022, "Polymeric dipicolylamine based mass tags for mass cytometry", https://doi.org/10.5683/SP3/WADUHE, Borealis, V1
Mass cytometry is an emerging powerful bioanalytical technique for high-dimensional single-cell analysis. In this technique, cells are stained with metal-isotope-tagged antibodies and are analyzed by an inductively coupled plasma time-of-flight mass spectrometer. While there are...
The role of cooling rate in crystallization-driven block copolymer self-assembly
Nov 23, 2021
Song, Shaofei; Jiang, Jingjie; Nikbin, Ehsan; Howe, Jane Y.; Manners, Ian; Winnik, Mitchell A., 2021, "The role of cooling rate in crystallization-driven block copolymer self-assembly", https://doi.org/10.5683/SP3/XLJEB7, Borealis, V1
This study focused on the effect of cooling rate following a heating step on the micelle morphologies formed by a series poly(ferrocenyldimethylsilane) (PFS) crystalline-coil block copolymers (BCPs) in solution. We employed transmission electron microscopy (TEM) (i.e. Figure 3) t...
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