Dataverse containing all unpublished research material authored by Ammar Sal.
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Transcriptome-based evaluation of the translatable potential of new treatments in Triple-Negative Breast Cancer
Transcriptome-based evaluation of the translatable potential of new treatments in Triple-Negative Breast Cancer
Sep 22, 2021
Salkini, Ammar; Wang, Lisheng, 2021, "Transcriptome-based evaluation of the translatable potential of new treatments in Triple-Negative Breast Cancer", https://doi.org/10.5683/SP3/JSMI9B, Borealis, V2
Full Abstract: Introduction: Triple-negative breast cancer (TNBC) is a highly metastatic type of breast cancer and one of the largest contributors to cancer mortality in women. Unlike other breast cancers, TNBC lacks any approved therapeutic targets. Scientists are rigorously att...
Review: Tau Biochemistry and Therapeutics in Alzheimer’ s Disease
Review: Tau Biochemistry and Therapeutics in Alzheimer’ s Disease
Sep 18, 2021
Salkini, Ammar, 2021, "Review: Tau Biochemistry and Therapeutics in Alzheimer’ s Disease", https://doi.org/10.5683/SP3/V4DJVA, Borealis, V1
Preface: The incidence of Alzheimer’s disease has been continuously increasing over the past two decades. This has significant implications to the quality of life of many individuals and their families, and also places a large financial burden on the healthcare system. The tau pr...
Post-translational Modifications of ATG16L1 are essential for the stability and activation of the Autophagosome Complex
Post-translational Modifications of ATG16L1 are essential for the stability and activation of the Autophagosome Complex
Sep 17, 2021
Salkini, Ammar; Losier, Truc To; Russell, Ryan, 2021, "Post-translational Modifications of ATG16L1 are essential for the stability and activation of the Autophagosome Complex", https://doi.org/10.5683/SP3/XL82K5, Borealis, V1
Autophagy is a cellular stress response pathway that controls cell growth and maintains homeostasis. Dysregulation of autophagy leads to several cytopathic disorders, such as cancer, inflammatory bowel disorders, and neurodegeneration. Cellular stress, such as nutrient starvation...
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