Contains subverses for various clinical studies who are collaborating with the CoLab. Contents for each study may include: protocols, standard operating procedures, data summaries, de-identified patient data, etc.
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1 to 10 of 53 Results
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Wiens, Matthew O.; Jacob, Shevin T.; Kabajaasi, Olive; Kenya Mugisha, Nathan, 2024, "Smart Discharges Program for children with sepsis in Uganda: a qualitative program evaluation", https://doi.org/10.5683/SP3/VAKMMD, Borealis, V1
Background: Pediatric sepsis continues to be a significant burden in low- and middle-income countries. Studies have shown that in-hospital mortality is equal to, and sometimes exceeds, mortality during the post-discharge period. These facts call for a concerted action to improve...
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Wiens, Matthew O; Toliva,Opar Bernard; Nsungwa-Sabiiti, Jesca; Mwaka, Savio; Komugisha, Clare; Nyalwal, Beatrice Lydiah Adhiambo; Bone, Jeffrey; Nguyen, Vuong; Kenya-Mugisha, Nathan, 2024, "Smart Discharges for vulnerable refugee children: a cohort study to validate prognostic algorithms for post-discharge readmission and mortality among children living in refugee settings", https://doi.org/10.5683/SP3/KCFQ9U, Borealis, V1
Background: In many African countries, pediatric post-discharge mortality following in-hospital treatment for severe infectious illness is higher than in-hospital mortality (5-8%). Risk algorithms can be used to help health workers identify those most vulnerable to poor post-disc...
Jul 22, 2024 - Smart Discharges - Manuscripts
Wiens, Matthew O; Tagoola, Abner; Kissoon, Niranjan; Ansermino, J Mark; Oyella Sherine, Sheila; Byaruhanga, Emmanuel; Ssemwanga, Edwards; Zhang, Cherri; Nguyen, Vuong; Bone, Jeffery N; Kenya Mugisha, Nathan; Kumbakumba, Elias; Kabakyenga, Jerome, 2024, "Smart Discharges to improve pediatric post-discharge survival", https://doi.org/10.5683/SP3/BGSQKD, Borealis, V1
Background: In Sub-Saharan Africa, pediatric post-discharge death is increasingly recognized as an important contributor to mortality. Current studies evaluating interventional approaches for post-discharge mortality focus on pharmacologic therapy, though only malaria prophylaxis...
Jul 22, 2024 - Smart Discharges - Study Protocols & Supplementary Materials
Umuhoza, Christian; Hooft, Anneka; Uwiragiye, Emmanuel; Kornblith, Aaron; Wiens, Matthew O, 2024, "Smart Discharges to improve post-discharge health outcomes in children in Rwanda", https://doi.org/10.5683/SP3/NTNTZX, Borealis, V1
Background: The Smart Discharges studies in Uganda have enrolled over 10,000 children under-five with sepsis and have shown that death after hospital discharge occurs in 5-8% of patients, which is as common as death during the primary admission. The Smart Discharges evidence-base...
Jul 16, 2024 - Smart Discharges - Manuscripts
Wiens, Matthew O; Nguyen, Vuong; Bone, Jeffrey N; Kumbakumba, Elias; Businge, Stephen; Tagoola, Abner; Sherine, Sheila Oyella; Byaruhanga, Emmanuel; Ssemwanga, Edward; Barigye, Celestine; Nsungwa, Jesca; Olaro,Charles; Ansermino, J Mark; Kissoon, Niranjan; Singer, Joel; Larson, Charles P; Lavoie, Pascal M; Dunsmuir, Dustin; Moschovis, Peter P; Novakowski, Stefanie; Komugisha, Clare; Tayebwa, Mellon; Mwesigwa, Douglas; Knappett, Martina; West, Nicholas; Kenya-Mugisha, Nathan; Kabakyenga, Jerome, 2024, "Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda: A multicohort analysis", https://doi.org/10.5683/SP3/M3OPKQ, Borealis, V1
Background: In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed t...
Jun 13, 2024 - Smart Triage - Manuscripts
Zhang, Cherri; Wiens, Matthew O; Dunsmuir, Dustin; Pillay, Yashodani; Huxford, Charly; Kimutai, David; Tenywa, Emmanuel; Ouma, Mary; Kigo, Joyce; Kamau, Stephen; Chege, Mary; Kenya-Mugisha, Nathan; Mwaka, Savio; Dumont, Guy A; Kisson, Niranjan; Akech, Samuel; Ansermino, J Mark, 2024, "Geographical validation of the Smart Triage Model by age group", https://doi.org/10.5683/SP3/4OI0BI, Borealis, V2
Background: Age is an important risk factor among critically ill children with neonates being the most vulnerable. Clinical prediction models need to account for age differences and must be externally validated and updated, if necessary, to enhance reliability, reproducibility, a...
Jun 12, 2024 - PALISI Global Health - Manuscripts
Kortz, Teresa B; Mediratta, Rishi; Smith, Audrey M; Nielsen, Katie R; Agulnik, Asya; Gordon Rivera, Stephanie; Reeves, Hailey; O'Brien, Nicole F; Hau Lee, Jan; Abbas, Qalab; Attebery, Jonah E; Bacha, Tigist; Bhutta, Emaan G; Biewen, Carter; Camacho-Cruz, Jhon; Munoz, Alvaro Coronado; DeAlmeida, Mary L; Domeryo Owusu, Larko; Fonseca, Yudy; Hooli, Shubhada; Johnson, Hunter C; Leimanis-Laurens, Mara; Mally, Deogratisu Nicholaus; McCarthy, Amanda M; Mutekanga, Andrew; Pineda, Carol; Remy, Kenneth E; Sanders, Sara C.; Tabor, Erica; Rodrigues Teixeira, Adriana; Qi Jyuee Want, Justin; Kissoon, Niranjan; Takwoingi, Yemisi; Wiens, Matthew O; Bhutta, Adnan, 2024, "Etiology of hospital mortality in children living in low-and middle-income countries: a systematic review and meta-analysis", https://doi.org/10.5683/SP3/2UKUKW, Borealis, V1, UNF:6:aiph6Iuwi9m6OKCXhI/QUQ== [fileUNF]
Background: In 2019, 80% of the 7.4 million global child deaths occurred in low- and middle-income countries (LMICs). Global and regional estimates of cause of hospital death and admission in LMIC children are needed to guide global and local priority setting and resource allocat...
PALISI Global Health - Manuscripts(University of British Columbia)
Jun 12, 2024PALISI - Global Health
PALISI - Global Health(University of British Columbia)
Jun 12, 2024PALISI
PALISI(PALISI Network)
Jun 12, 2024
The Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI Network) specializes in identifying preventive, therapeutic, and preventive strategies for acute respiratory distress syndrome, sepsis, multi-organ failure, and other acute, life-threatening pulmonary or sys...
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